Publications

Publication

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1. Aarti Mishra, Yuan Shang, Yiwei Wang, Eliza R Bacon, Fei Yin, Roberta Brinton(2020). Dynamic Neuro-Immune Profile During Mid-life Aging in the Female Brain and Implications for Alzheimer’s Risk.iScience 2020. 23(12): p.101829.
2. Yuan Shang, Aarti Mishra, Tian Wang, Yiwei Wang, Maunil Desai, Shuhua Chen, Zisu Mao, Loi Do, Adam S. Bernstein, Theodore P. Trouard, and Roberta Brinton(2020). Evidence in Support of Chromosomal Sex Influencing Plasma Based Metabolome vs APOE Genotype Influencing Brain Metabolome Profile in Humanized APOE Male and Female Mice. PLoS One 2020 , 15(1):e0225392
3. Yiwei Wang, Yuan Shang, Aarti Mishra, Eliza Bacon, Fei Yin, Roberta Brinton(2020). Midlife chronological and endocrinological transitions in Brain Metabolism: System Biology Basis for increased Alzheimer’s Risk in female Brain. Sci. Rep. 10: 8528 (2020)
4. Zhuangfeng Weng, Yuan Shang, Zeyang Ji, Fei Ye, Lin Lin, Rongguang Zhang and Jinwei Zhu (2018). Structural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling. J. Am. Soc. Nephrol., 29 (9), 2362-2371
5. Yue Wang, Yuan Shang, Jianchao Li, Weidi Chen, Gang Li, Jun Wan, Wei Liu, Mingjie Zhang (2018). Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions. eLife 2018;7:e35677
6. Zhuangfeng Weng, Yuan Shang, Deqiang Yao, Jinwei Zhu, Rongguang Zhang (2018). Structural analyses of key features in the KANK1/KIF21A complex yield mechanistic insights into the crosstalk between microtubules and the cell cortex. J Biol Chem 293 (1), 215-225
7. Lei Zhang, Angela Jablonski, Jelena Mojsilovic-Petrovic, Hua Ding, Steven Seeholzer, Ian Newton, Inke S. Nathke, Rachael Neve, Jinbin Zhai, Yuan Shang, Mingjie Zhang, and Robert Kalb (2017). SAP97 binding partner CRIPT promotes dendrite growth in vitro and in vivo. eNeuro 4(6): ENEURO.0175-17
8. Jinwei Zhu, Qingqing Zhou, Yuan Shang, et al (2017). Synaptic targeting and function of SAPAPs mediated by phosphorylation-dependent binding to PSD-95 MAGUKs. Cell Report, 21 (13), 3781-3793
9. Vincent Gardeux, Joanne Berghout, Ikbel Achour A, Grant Schissler, Qike Li, Colleen Kenost, Jianrong Li, Yuan Shang, et al. (2017). A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations. J Am Med Inform Assoc 24, 1116-1126.
10. Yitian Xia, Yuan Shang, Rongguang Zhang, Jinwei Zhu (2017). Structure of the PSD-95/MAP1A complex reveals a unique target recognition mode of the MAGUK GK domain. Biochem J 474, 2817-2828
11. Jinwei Zhu, Yuan Shang*, Yitian Xia, Rongguang Zhu, et al. (2016). An Atypical MAGUK GK Target Recognition Mode Revealed by the Interaction between DLG and KIF13B. Structure 24,1-10.
12. Menglong Zeng, Yuan Shang, Yoichi Araki, Tingfeng Guo, et al. (2016). Phase transition in postsynaptic densities underlies formation of synaptic complexes and synaptic plasticity. Cell 166,1163-1175.
13. Menglong Zeng, Yuan Shang, Tingfeng Guo, Qinghai He, et al. (2016). A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function. Proc Natl Acad Sci USA 113, E3081-3090.
14. Jinwei Zhu, Yuan Shang, and Mingjie Zhang (2016). Mechanistic basis of MAGUK-organized complexes in synaptic development and signalling. Nat Rev Neurosci 17, 209-223.
15. Fei Ye, Wei Liu, Yuan Shang, and Mingjie Zhang (2016). An Exquisitely Specific PDZ/Target Recognition Revealed by the Structure of INAD PDZ3 in Complex with TRP Channel Tail. Structure 24, 383-391.
16. Jinwei Zhu, Yuan Shang, Qingwen Wan, Yitian Xia, et al. (2014). Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl. Cell Res 24, 451-463.
17. Zhu Pan, Jinwei Zhu, Yuan Shang*, Zhiyi Wei, et al. (2013). An Autoinhibited Conformation of LGN Reveals a Distinct Interaction Mode between GoLoco Motifs and TPR Motifs. Structure 21, 1007-1017.
18. Zhu Pan, Yuan Shang, Min Jia, Lu Zhang, et al. (2013). Structural and Biochemical Characterization of the Interaction between LGN and Frmpd1. J Mol Biol 425, 1039-1049.
19. Jinwei Zhu, Yuan Shang, Jia Chen, and Mingjie Zhang (2012). Structure and function of the guanylate kinase-like domain of the MAGUK family scaffold proteins. Front Biol 7, 379-396.
20. Chihao Wang, Yuan Shang, Jiang Yu, and Mingjie Zhang (2012). Substrate Recognition Mechanism of Atypical Protein Kinase Cs Revealed by the Structure of PKC¹ in Complex with a Substrate Peptide from Par-3. Structure 20, 791-801.
21. Jinwei Zhu, Yuan Shang, Caihao Xia, Wenning Wang, et al. (2011). Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho‐protein‐binding modules. EMBO J 30, 4986-4997.
22. Jinwei Zhu, Wenyu Wen, Zhen Zheng, Yuan Shang, et al. (2011). LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways. Mol Cell 43, 418-431.
23. Wenfu Ma, Yuan Shang, Zhiyi Wei, Wenyu Wen, et al. (2010). Phosphorylation of DCC by ERK2 Is Facilitated by Direct Docking of the Receptor P1 Domain to the Kinase. Structure 18, 1502-1511.

*:Co-first authors